Nonirritating compositions containing organic compounds which irritate the skin



Patented Aug. 25, 1931 UNITED STATES PATENT oFF-Ic E 1 rumourv ENG-ELHARDT, or LEVERKUSEN-ON-THERHINE, w w

I. e. FARBENINDUSTBIE AKTIENGESELLSCHAFT, or FBANKFORT-ON-THEl-MAIN,

GERMANY NONIRRITATING comrosrrrons coiv'rammeoneeivrc coiv'rrounns w II cII Inm'rn m GERMANY, Assrcmox n0 THE SKIN No Drawing. Application filed March so, 1927, Serial No. 17 9,7 23, and. in Germany April 12, 1926.

It is known that certain organic compounds whlch are used for mou1d1ng,1nsulating, mpregnating and analogous purposes and 1n moulding, Insulating, Impregnatmg and other compositions which are manipugas masks, especially designed clothing and the like which are expensive and inconvenient.

An object of the present invention is to render the irritating organic compounds nonirritating without destroying the properties upon which their usefulness depends. This may be accomplished, as I have found, by mixing the irritating compounds with nonirritating materials having similar physical properties. Among the non-irritating materials suitable for use generally may be mentioned parafiin wax, ceresine wax, pitch, rubber and the like. Only a relatively small quantity of the non-irritating material is required, i. e., the irritating action of the organic compounds may be substantially reduced or entirely prevented by the addition of a quantity of anon-irritating adulterant having similar physical properties which is insuflicient to materially alter the properties of the irritating compound.

I have also found that the irritating action of organic compounds generally may be materially reduced or substantially destroyed by means of agents having an alkaline action, such as sodium phosphate, calcium oxide, magnesium oxide, pyridine, tetrahydroquinaldine, urea and the like, which alkaline materials are efl'ective when used in quantities insufficient to materially affect the physical properties of the irritating organic compounds. The combined effects of additions of 1 Example 4. partsby weight of tetranon-irritating diluents, suchas paraflin wax and substances having an alkaline action, such as sodium phosphate, may be obtained by the use ofsubstances of both types.

The following examples are illustrative:

Example 1. 100 parts by weight of tetrachlornaphthalene, an irritating organic compound, are mixed by stirring for Several hours withabout 7 parts byweight of pitch. The physical properties of the product are substantiallythe' same as those of tetrachlornaphthalene but the product is not irritating to the skin.

E arample I2. '100 parts by weight of tetrachlornaphthalene. are mixed by stirring for several hours'with 10 parts by weight of mag nesium oxide. The product is non irritating and has the desired physical properties.

' Ewample. 100 parts byweight of tetrachlornaphthalene are mixed by stirring for several hours with 10 parts. by weight of paraflin wax and5 parts by weight of magneslum oxide' The product is non-irritatmg and has the desired physical properties.

chlorotoluol are fused whilst stirring together with 9 parts by weight of pitch and 2 partsby weightxof-urea. 1 I

' It will be understood. that the foregoing examples are merely illustrative. What may be done with tetrachlornaphthalene by the use of pitch, parafiin wax and'magnesium oxide may also be done with other irritating organic compounds by the use of other non irritating plastic organic material such as ceresine wax, rubber, etc. and other compounds having an alkaline action such as sodium phosphate, urea, etc.

I claim:

1. As a new product a non-irritating com- 5 position of matter comprising a halogenated naphthalene which is irritating to the Skin and is used for moulding, insulating, impregnating and similar purposes intimately mixed with a relatively small amount of a 5 position of mattercomprising a halogenated 1 o naphthalene which is irritating to the skin and is used for moulding, insulating, impregnating and similar purposes intimately mixed with relatively small amounts of a 5 material of the group consisting of organic bases, alkaline earth metal oxides and basic reacting salts and a non-irritating plastic organic material of the group consisting of wax, pitch, rubber and resin.

3. As a new product a non-irritating composition comprising a halogenated naphthalene which is irritating to the skin intimately mixed with a relatively small amount of magnesium oxide.

4. As a new product a non-irritating c0mposition comprising a halogenated naphthalene which is irritating to the skin intimately mixed with relatively small amounts of a magnesium oxide and a non-irritating plastic 0 organic material of the group consisting of wax, pitch, rubber and resin.

5. As a new product a non-irritating composition comprising a tetrachlornaphthalene which is irritating to the skin intimately mixed with a relatively small amount of a material of the group consisting of organic bases, alkaline earth metal oxides and basic reacting salts.

6. As a new product a non-irritating com- 3 position comprising a tetrachlornaphthalene which is irritating to the skin intimately mixed with relatively small amounts of a material of the group consisting of organic bases, alkaline earth metal oxides and basic 3; reacting salts and a non-irritating plastic organic material of the group consisting of wax, pitch, rubber and resin.

7. As a new product a non-irritating composition comprising a tetrachlornaphthalene which is irritating to the skin intimately mixed with a relatively small amount of magnesium oxide.

8. As a new product a non-irritating composition comprising a tetrachlornaphthalene $6 which is irritating to the skin intimately mixed with a relatively small amount of magnesium oxide and a relatively small amount of parafiin wax.

In testimony whereof, I afiix m signature.

to RUDOLF ENGEL ARDT. 

